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    Micromedex Consumer Medication Information.
    Uses Uses of This Medicine Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors . These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly.
    The penis is one of the areas where this enzyme works.
    Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection.

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    By controlling the enzyme , sildenafil helps to maintain an erection after the penis is stroked.
    Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection.
    Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels . This will increase the supply of blood to the lungs and reduce the workload of the heart.
    How To Use Tablet, Liquid Your doctor will tell you how much medicine to use.
    Do not use more than directed.
    For erectile dysfunction: Take this medicine about 1 hour before you have sex.
    Do not take it more than once a day.
    Always allow at least 24 hours between doses.
    For pulmonary arterial hypertension : Take this medicine 3 times a day, 4 to 6 hours apart.
    If you miss a dose, take it as soon as you remember.

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