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    Viagra (sildenafil) is used to treat erectile dysfunction or impotence in men. Includes Viagra side effects, interactions and indications.

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    Viagra: Sildenafil belongs to a group of medications called phosphodiesterase type 5 inhibitors. It is used for the treatment of erectile dysfunction (male impotence).

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    Viagra®sildenafil citrateConsumer Medicine InformationWhat is in this leafletThis leaflet answers some common questions about Viagra.It does not contain all the available information.It does not take the place of talking to your doctor or pharmacist.All medicines have risks and benefits.

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    See full prescribing information for VIAGRA. VIAGRA (sildenafil citrate) tablets, for oral use Initial U.S. Approval: 1998 RECENT MAJOR CHANGES Warnings and Precautions, Effects on the Eye ( 5.3 ) 08/2017 INDICATIONS AND USAGE VIAGRA is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) ( 1 ) DOSAGE AND ADMINISTRATION For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity.
    However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1 ) Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1 ) Maximum recommended dosing frequency is once per day ( 2.1 ) DOSAGE FORMS AND STRENGTHS Tablets: 25 mg, 50 mg, 100 mg ( 3 ) CONTRAINDICATIONS Administration of VIAGRA to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form.
    VIAGRA was shown to potentiate the hypotensive effect of nitrates ( 4.1 , 7.1 , 12.2 ) Known hypersensitivity to sildenafil or any component of tablet ( 4.2 ) Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3 ) WARNINGS AND PRECAUTIONS Patients should not use VIAGRA if sexual activity is inadvisable due to cardiovascular status ( 5.1 ) Patients should seek emergency treatment if an erection lasts 4 hours.
    Use VIAGRA with caution in patients predisposed to priapism ( 5.2 ) Patients should stop VIAGRA and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). VIAGRA should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION. ( 5.3 ) Patients should stop VIAGRA and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4 ) Caution is advised when VIAGRA is co-administered with alpha-blockers or anti-hypertensives.
    Concomitant use may lead to hypotension ( 5.5 ) Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures.
    In patients taking strong CYP inhibitors, such as ritonavir, sildenafil exposure is increased.
    Decrease in VIAGRA dosage is recommended ( 2.4 , 5.6 ) ADVERSE REACTIONS Most common adverse reactions ( 2%) include headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Pfizer at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.
    Increase VIAGRA exposure ( 2.4 , 7.4 , 12.3 ) Ritonavir: Do not exceed a maximum single dose of 25 mg in a 48 hour period ( 2.4 , 5.6 ) Erythromycin or strong CYP3A4 inhibitors (e.
    Consider a starting dose of 25 mg ( 2.4 , 7.4 ) USE IN SPECIFIC POPULATIONS Geriatric use: Consider a starting dose of 25 mg ( 2.5 , 8.5 ) Severe renal impairment: Consider a starting dose of 25 mg ( 2.5 , 8.6 ) Hepatic impairment: Consider a starting dose of 25 mg ( 2.5 , 8.7 ) See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.

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    However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity.
    The maximum recommended dosing frequency is once per day.
    Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg.
    Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold . 2.5 Dosage Adjustments in Special Populations Consider a starting dose of 25 mg in patients 65 years, patients with hepatic impairment (e.
    L/minute) because administration of VIAGRA in these patients resulted in higher plasma levels of sildenafil . 3 DOSAGE FORMS AND STRENGTHS VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil.
    Tablets are debossed with PFIZER on one side and VGR25, VGR50 or VGR100 on the other to indicate the dosage strengths.
    After patients have taken VIAGRA, it is unknown when nitrates, if necessary, can be safely administered.
    Although plasma levels of sildenafil at 24 hours post dose are much lower than at peak concentration, it is unknown whether nitrates can be safely co-administered at this time point . 4.2 Hypersensitivity Reactions VIAGRA is contraindicated in patients with a known hypersensitivity to sildenafil, as contained in VIAGRA and REVATIO, or any component of the tablet.
    Hypersensitivity reactions have been reported, including rash and urticaria . 4.3 Concomitant Guanylate Cyclase (GC) Stimulators Do not use VIAGRA in patients who are using a GC stimulator, such as riociguat.
    PDE5 inhibitors, including VIAGRA, may potentiate the hypotensive effects of GC stimulators.

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